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ISSUE 1617
ISSUE 1617
February 8, 2021
Osilodrostat (Isturisa) for Cushing's Disease
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February 8, 2021 (Issue: 1617)
The FDA has approved osilodrostat (Isturisa –
Recordati), a cortisol synthesis inhibitor, for oral
treatment of adults with Cushing's disease when
surgical resection of the pituitary adenoma is not an
option or has not been curative. Osilodrostat is the
first cortisol synthesis inhibitor to be approved in
the US for this indication. Other oral steroidogenesis
inhibitors such as ketoconazole and metyrapone have
been used off-label for this indication for many years.
... more

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Title: Osilodrostat (Isturisa) for Cushing's Disease
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